mesenchymal stem cells from umbilical cord tissue as potential therapeutics for cardiomyodegenerative diseases – a review
نویسندگان
چکیده
heart failure is one of the leading causes of death worldwide. end stage disease often requires heart transplantation, which is hampered by donor organ shortage. tissue engineering represents a promising alternative approach for cardiac repair. for the generation of artificial heart muscle tissue several cell types, scaffold materials and bioreactor designs are under investigation. in this review, the use of mesenchymal stem cells derived from human umbilical cord tissue (ucmsc) for cardiac tissue engineering will be discussed.
منابع مشابه
Mesenchymal stem cells from umbilical cord tissue as potential therapeutics for cardiomyodegenerative diseases – a review
Heart failure is one of the leading causes of death worldwide. End stage disease often requires heart transplantation, which is hampered by donor organ shortage. Tissue engineering represents a promising alternative approach for cardiac repair. For the generation of artificial heart muscle tissue several cell types, scaffold materials and bioreactor designs are under investigation. In this revi...
متن کاملMesenchymal stem cells from umbilical cord tissue as potential therapeutics for cardiomyodegenerative diseases – a review
Heart failure is one of the leading causes of death worldwide. End stage disease often requires heart transplantation, which is hampered by donor organ shortage. Tissue engineering represents a promising alternative approach for cardiac repair. For the generation of artificial heart muscle tissue several cell types, scaffold materials and bioreactor designs are under investigation. In this revi...
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The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues such as bone marrow and connective tissues has provided exciting prospects for cell-based tissue engineering and regeneration. This review article focuses on the biology of MSCs, their differentiation potentials in vitro and in vivo, and their application in tissue engineering...
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Umbilical cord blood (UCB) has been used for transplantation in the treatment of hematologic disorders as a source of hematopoietic stem cells (HSCs). Because of insufficient number of cord blood CD34+ cells, the expansion of these cells seems to be important for clinical application. Mesenchymal stromal cells (MSCs), playing an important role in HSCs maintenance, were used as feeder layer. Apo...
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عنوان ژورنال:
international journal of molecular and cellular medicineجلد ۱، شماره ۳، صفحات ۱۱۹-۱۳۲
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